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4,5 The reality is, the mechanism of action is likely much more complex than we currently appreciate, involving multiple channels and even alterations in gene regulation

Biomarker Development : There is a need for valid biomarkers of lipid peroxidation and ferroptosis for patient characterization as well as ferritin assays monitoring

However, there are little data about targeting metabolic changes in RA

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METH significantly increased calpain-specific spectrin breakdown products, and this increase was prevented with lactulose treatment